Chemo Immuno Precision Injections (CIPI™)

Envita Medical Centers’ CIPI™ procedure could be a breakthrough for end-stage and complex cancers


For the last 20 years, Envita Medical Centers has been focused on improving patient outcomes by providing advanced, patient-specific treatment options that take precision targeting to the next level. Envita is proud to present a precision form of tumor chemoembolization called Chemo Immuno Precision Injections, or CIPI™, as an advanced treatment method for fibrous tumors that are difficult to penetrate through traditional intravenous chemotherapy treatment. CIPI™ has the potential to revolutionize the treatment of pancreatic cancer and other difficult forms of cancer where surgery is not a viable option.

This video is for informational purposes only. Individual results will vary. Envita makes no guarantees. Consult with your doctor to see if CIPI™ is right for you. Not every patient is a candidate for Chemo Immuno Precision Injection. Some cancers may not have actionable biomarkers or molecular profiles. Do not alter your medical care based on any information provided in this video. Please, consult your doctor prior to changing or stopping any current medical treatment you are receiving.

By combining our unique personalized treatment protocols with the accuracy and increased precision of direct injection interventional radiology, we are approaching a new frontier in cancer treatment. CIPI™ represents the latest advancements in cancer treatment and delivery, helping us realize our goal of always providing our patients with the latest in cancer treatment technology and techniques so we can continue to give our patients the greatest chance to respond to care.

This video is for informational purposes only. Individual results will vary. Envita makes no guarantees. Consult with your doctor to see if CIPI™ is right for you. Not every patient is a candidate for Chemo Immuno Precision Injection. Some cancers may not have actionable biomarkers or molecular profiles. Do not alter your medical care based on any information provided in this video. Please, consult your doctor prior to changing or stopping any current medical treatment you are receiving.

What Is a Chemo Immuno Precision Injection?

CIPI™ is a procedure is a procedure performed at our Envita Interventional Radiology facility (EnvitaIR™). The CIPI™ procedure harnesses the latest in advanced patient-specific genomic data which is used to create customized immunotherapy treatments that are combined with adjuvant agents and deployed directly inside the tumors of concern.

CIPI™ is a minimally invasive procedure that utilizes a catheter no thicker than a human hair which is fed from an appropriate vessel through the body and into the cancerous tumor. The personalized, micro-dosed, combination of genetically targeted medications are injected directly into the tumor allowing for increased medication delivery and reduced side-effects. By directly injecting medications into the tumor, we can potentially achieve maximum exposure of the genetically targeted medications to the tumor making it one of the most powerful methods of medication delivery. The blood supply to the tumor is then sealed off to help improve the effectiveness of the medications with precise agent delivery.

This video is for informational purposes only. Individual results will vary. Envita makes no guarantees. Consult with your doctor to see if CIPI™ is right for you. Not every patient is a candidate for Chemo Immuno Precision Injection. Some cancers may not have actionable biomarkers or molecular profiles. Do not alter your medical care based on any information provided in this video. Please, consult your doctor prior to changing or stopping any current medical treatment you are receiving.

Envita’s Treatment Selection Process

The CIPI™ procedure would just be run-of-the-mill chemoembolization if it were not for our development of a treatment selection process that utilizes genetic information designed to personalize the treatment protocol with the chemo genetic and immune genetic targets discovered from not only your tumor, but your unique genetic make-up.

By examining your miRNA, circulating tumor cell DNA, and tumor mutations, Envita’s in-house custom pharmacy develops a targeted treatment in combination with adjunctive supportive agents to enhance the actions of the drug. This targeted and genetically driven treatment can work to not only attack your tumor but may also activate your immune system to actively attack free circulating cancer cells.

The immune system is designed to seek and destroy cancerous cells and Envita Medical Centers’ treatment selection process is designed to identify and upregulate your immune system to provide a multifaceted approach to targeting and fighting your cancer.

Potential Advantages of CIPI™

CIPI™ is a minimally invasive targeted procedure for patients who cannot undergo surgical tumor removal for a multitude of reasons. Surgery can be very detrimental to certain patients because surgery stresses the body and suppresses the immune system. The risks of surgery become even greater when dealing with a complex or end-stage cancer.

The CIPI™ procedure was designed for cancers that originate in dense tissues that traditional intravenous chemotherapy has a difficult time penetrating, like pancreatic and liver cancer, but we have seen clinically CIPI™ be an option for any cancer that is a solid tumor.

Traditional intravenous chemotherapy delivers maximum doses of chemotherapeutic agents throughout the entire body but only a small percentage is estimated to reach the tumors it is meant to target. With the targeted medications being directly delivered into the tumor’s themselves, and the blood supply sealed off, there is potentially a greater chance for improved patient response.

Because the procedure is performed through a single catheter that is fed through the body’s circulatory system directly to the tumor, the incision site is very minor, patient’s leave with a single bandage on their wound while still receiving maximum drug delivery allowing for quicker healing.

The goal of the CIPI™ procedure is to revolutionize patient care where the standard of care protocol is not enough or where the patient has failed other therapies and needs precision options to explore. The highly targeted nature of the CIPI™ procedure is proving to be a possible alternative and we are excited to have developed this technology to help our patients thrive.

If you have any questions about the CIPI™ procedure or are curious if you would be a candidate, please contact our Patient Care Coordinator team at 866-830-4576. Our trained professionals are standing by to help you discover if CIPI™ is right for you. May God bless you on your journey to healing!

Disclaimer: Envita makes no guarantees. Consult with your doctor to see if CIPI TM is right for you. Not every patient is a candidate for Chemo Immuno Precision Injection. Some cancers may not have actionable biomarkers or molecular profiles. Do not alter your medical care based on any information provided in this article. Please, consult your doctor prior to changing or stopping any current medical treatment you are receiving.

To better understand our unique approach to cancer treatment: