The Critical Factors to Proper Lyme Disease TreatmentBy ENVITA MEDICAL CENTER
Over a decade of researching the causes of numerous chronic diseases has led to the realization that tick-borne infections such as Borrelia burgdorferi, the spirochete responsible for Lyme disease, and its many co-infections are consistently present in patients suffering with chronic disease. Chronic Lyme disease is the primary culprit behind these debilitating symptoms, but treating the resistant co-infections can be just as difficult as treating Lyme because this group of infections has highly advanced survival mechanisms.
Over fifteen years of research and clinical experience has led to the publication of several important papers on the subject. The first of which being published in 2014 in the Open Journal of Medical Microbiology titled, “Borrelia burgdorferi: Cell Biology and Clinical Manifestations in Latent Chronic Lyme,” explains how Borrelia burgdorferi is one of the most complex and advanced bacterial infections in the world. Borrelia has the evasive ability to shift its antigens which makes it difficult for the immune system to locate and rid the body of this invasive bacteria. Its resistance to antibiotics, traditional treatments, and natural treatments is what makes Chronic Lyme Disease Complex inherently difficult to treat. Borrelia causes chronic inflammation to the joints, muscles, and brain cells, creating pain and damage to the neurological system while causing many psychiatric imbalances. The source of Borrelia's destructive power is found in the release of endotoxins and neurotoxins which destroy muscle and nerve fibers throughout the body. The reason most patients fail treatment is because one of many key factors is not being properly addressed. These factors require extreme in-depth coverage and highly personalized targeted treatments to help the patient finally get well.
When these key factors of Lyme disease treatment are not properly addressed, the patient will struggle with the reoccurrence of disease and be left with failed long-term results.
Often times Lyme disease patients will have been examined by multiple specialists including neurologists, gastroenterologists, rheumatologists, chiropractors, naturopaths, and multiple Lyme literate doctors. These specialists may bring about short-term symptom reduction but rarely lead to long-term results.
Listed below are the critical factors that must be addressed to help patients finally reach optimal health.
- Getting a more complete and accurate diagnosis is key. Typically, patients present with a wide range of primary and secondary infections which display unique symptoms to their specific condition. These infections will include bacterial, viral, fungal, and parasitic infections, therefore a complete diagnosis is essential to select which treatments are necessary to attack all of the existing infections that are present in the patient's body. Weakened immunity caused by the multitude of infections in the body will often lead to patients receiving false negative test results. Traditional Lyme disease tests rely on the body's production of antibodies to yield a positive result. The compromised immune state in patients suffering with chronic disease interferes with the body's production of these antibodies. Therefore, a patient's history and full symptom intake is essential for proper treatment. Be aware that there are areas of the country that do not recognize Lyme disease as a condition and testing is not even conducted, let alone properly executed. Remember Chronic Lyme disease involves multiple types of infections and they must all be properly diagnosed to allow for effective treatment.
- It is common for chronic Lyme disease infections to have MDR (multi-drug resistance), this resistance renders standard treatments like antibiotics and many natural therapies ineffective. This resistance is why most standard treatments will often affect the symptoms for a short span of time and then suddenly stop working. The infections found in Chronic Lyme Disease Complex, especially Borrelia burgdorferi, have specialized pumps called P-gp (p-glycoprotein), that literally pump out medication and supplements as a survival method for the organism. At the same time Borrelia is resisting drugs, it is also shifting its surface antigens, effectively eluding attacks from the body's own immune system. These evasive abilities are why Borrelia burgdorferi is being described as a superbug. Multi-drug resistance has become a very serious problem in many infectious categories. Groups like WHO (World Health Organization) and the CDC (Centers for Disease and Control) have spoken and published on this problem extensively.
- The brain has a highly selective permeable barrier called the Blood-Brain Barrier that normally protects the brain from foreign invaders but Borrelia's unique characteristics allow it to penetrate this protective barrier. Neurological symptoms are present with Chronic Lyme Disease Complex, often times because Borrelia and its endotoxins are located in the brain and central nervous system causing inflammation, damage, and various neurological problems such as tremors, seizures, brain fog, chronic headaches, and pain. Therefore, medications have to be delivered and passed through the blood-brain barrier to safely treat these infections while not harming the patient.
- These infections tend to collect and protect themselves in Biofilm Communities, biofilm works to stop the immune system and medications, like antibiotics, from reaching their target. Biofilm is a protective sludge that surrounds the infections and allows the infectious organisms to release chemicals and endotoxins to destroy nerve and muscle tissue and overtime expand the colony of infections. Striping biofilm correctly allows treatments to be much more effective by disabling one of the infections primary defenses.
- Flushing endotoxins that are released form Borrelia is also a difficult task because it involves liver metabolism and detoxification pathways. Many patients with metabolic issues, also known as, Inborn Errors of Metabolism have a hard time eliminating the waste of endotoxins that are stuck to nerve and hormone receptors throughout the body. This correction to the patient's elimination process is critically important to healing.
- Patients on pain medication and other narcotics have made it even more difficult to heal because many of the drugs (pain killers, psychiatric, anti-anxiety) are suppressive in nature and compete with the body's normal neurotransmitters and hormone receptor sites. The best example here is trying to fit multiple keys into the same keyhole all at the same time. Medications that treat symptoms and not the cause of these symptoms compete with treatments that need these receptor sites to be effective, this process complicates treatment significantly. Properly modifying medications and putting the correct treatment plan in place is essential.
- Reestablishing the immune system is important as patients with these infections have depressed immune states and become opportunistic to many other infections. This is why bacterial, viral, fungal, and parasitic infections will all be present at the same time. Treatment must include targeting natural killer cells, cytokines, and other essential parts of the immune system so that the patient can rebuild their own immune defenses for long-term success.
- Endotoxin complications are responsible for the vast majority of symptoms related to Chronic Lyme Disease. Patients present with a wide variety of symptoms; joint pain, brain fog, blood clotting problems, depression, anxiety, tremors, seizures to name a few. The reason the symptoms of Lyme Disease can mimic over 360 different diseases is because endotoxins are invasive and destroy multiple tissue types and immunity. The endotoxins are what Borrelia releases to kill its host. In fact, during treatment when Borrelia is killed off, microbursts of endotoxins cause the famous Herxhiemer reaction that is seen in so many patients. Endotoxins need to be flushed and eliminated properly throughout the process of treatment so that the patient can experience overall improvement.
Biofilm Protecting Borrelia and its Co-Infections from the Immune System and Antibiotics
With Chronic Lyme Disease Complex there are many unique complications and presentations to consider. This is why patients don't respond to most treatments long-term and why patients need highly personalized treatments to addresses all factors involved in their case. If you have any questions about Lyme disease or this article don't hesitate to ask us. We have a dedicated team who can help answer any specific questions you may have as well as provide more in-depth educational material to help you make the right decisions when it comes to proper chronic Lyme disease treatment.
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